Searchable abstracts of presentations at key conferences in endocrinology

ea0042p26 | (1) | Androgens2016

Mechanisms behind tumor relapse in 22Rv1 xenografts after treatment with abiraterone or cabazitaxel

Ylitalo Erik Bovinder , Wikstrom Pernilla

Castration-resistant prostate cancer (CRPC) develops after androgen deprivation therapy of advanced PC, often with metastatic growth in bone and very poor prognosis. Standard treatment is docetaxel, followed by androgen-synthesis (abiraterone) or androgen receptor inhibition, or treatment with the novel taxane cabazitaxel. Novel drugs are constantly under development and molecular properties of individual tumors will determine treatment effectiveness in individual cases. The a...